Journal Articles
publications
2025
Kim JH, Yoon HJ, Choi Y, Kim JS, Ju IG, Eo H, et al. 6-Shogaol, a neuro-nutraceutical derived from ginger, alleviates motor symptoms and depression-like behaviors and modulates the release of monoamine neurotransmitters in Parkinson's disease mice. Eur J Nutr. 2025;64:116.
Kim JH, Kim JS, Eo H, Yang S, Lee CH, Park SA, et al. Streptomyces rimosus-rich soil exposure alleviates depression-like behaviors by modulating neuroinflammation and synaptic plasticity in mice with stress. Sci Rep. 2025;15:28117.
Ju IG, Lee S, Im H, Kim JH, Eo H, Oh MS. Artemisiae Iwayomogii Herba mitigates excessive neuroinflammation and Abeta accumulation by regulating the pro-inflammatory response and autophagy-lysosomal pathway in microglia in 5xFAD mouse model of Alzheimer's disease. Geroscience. 2025;47:1957-72.
Ju IG, Lee JH, Lee JM, Im H, Eo H, Moon M, et al. NXP031 restores memory function by dual effects degrading Abeta accumulation and facilitating antioxidant pathway in Alzheimer's disease models. Free Radic Biol Med. 2025;226:158-70.
Eo H, Park J, Ju IG, Oh MS. 6-shogaol, a bioactive component of ginger, alleviates aging-induced ocular inflammation and ER stress in the 25-month-old mice. J Nutr Biochem. 2025;144:109980.
Eo H, Kim SH, Ju IG, Lee JH, Oh MS, Kim YJ. NXP032 Improves Memory Impairment Through Suppression of Tauopathy in PS19 Mice and Attenuates Okadaic Acid-Induced Tauopathy in SH-SY5Y Cells. J Neuroimmune Pharmacol. 2025;20:10.
Choi Y, Choi JG, Huh E, Eo H, Shin YJ, Park MG, et al. Lactobacillus taiwanensis BCRC17755 alleviates motor dysfunction and dopaminergic neuronal loss in mouse models of Parkinson's disease. Benef Microbes. 2025;16:413-23.
2024
Reed CH, Tystahl AC, Eo H, Buhr TJ, Bauer EE, Lee JH, et al. The Influence of Stress and Binge-Patterned Alcohol Drinking on Mouse Skeletal Muscle Protein Synthesis and Degradation Pathways. Biomolecules. 2024;14.
Md S, Hong SM, Lee JH, Park H, Chang KA, Kim HB, Park MG, Eo H et al. Depression like-behavior and memory loss induced by methylglyoxal is associated with tryptophan depletion and oxidative stress: a new in vivo model of neurodegeneration. Biol Res. 2024;57:87.
Lee S, Ju IG, Eo H, Kim JH, Choi Y, Oh MS. Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-beta induced neuritic dystrophy in 5xFAD mouse. Chin Med. 2024;19:95.
Kim JS, Kim JH, Eo H, Ju IG, Son SR, Kim JW, et al. Inulae Flos has Anti-Depressive Effects by Suppressing Neuroinflammation and Recovering Dysfunction of HPA-axis. Mol Neurobiol. 2024;61:8038-50.
Kim JH, Huh E, Eo H, Kim JS, Kwon Y, Ju IG, et al. Tribuli Fructus alleviates 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease by suppressing neuroinflammation via JNK signaling. Metab Brain Dis. 2024;40:69.
Kim J, Hee Kim J, Woo Seo E, Kim Y, Kang J, Woo Koh C, Ju IG, Eo H et al. Polymeric amino-single-benzene nano-aggregates (PANA) as a Next-Generation glioblastoma photodynamic therapy. Chemical Engineering Journal. 2024;479:147703.
Ju IG, Lee S, Kim SH, Im H, Eo H, Oh MS. Trichosanthis Semen Exerts Neuroprotective Effects in Alzheimer's Disease Models by Inhibiting Amyloid-beta Accumulation and Regulating the Akt and ERK Signaling Pathways. J Alzheimers Dis. 2024;98:119-31.
Eo H, Yu SH, Choi Y, Kim Y, Kang YC, Lee H, et al. Mitochondrial transplantation exhibits neuroprotective effects and improves behavioral deficits in an animal model of Parkinson's disease. Neurotherapeutics. 2024;21:e00355.
Eo H, Hee Kim J, Im H, Gyoung Ju I, Huh E, Pun R, et al. 6-Shogaol attenuates natural aging-induced locomotive and cognitive declines through suppression of p75 neurotrophin receptor in vivo. Journal of Functional Foods. 2024;113:106025.
2023
Krishna S, Echevarria KG, Reed CH, Eo H, Wintzinger M, Quattrocelli M, et al. A fat- and sucrose-enriched diet causes metabolic alterations in mdx mice. Am J Physiol Regul Integr Comp Physiol. 2023;325:R692-R711.
Kim SH, Ju IG, Kim JH, Eo H, Son SR, Jang DS, et al. Linderae Radix Ameliorates Cognitive Dysfunction by Inhibiting Neuroinflammation and Synaptic Damage in Alzheimer's Disease Models. Mol Neurobiol. 2023;60:7196-207.
Kim JH, Jin S, Eo H, Oh MS, Lim Y. Two Faces of Catechol-O-Methyltransferase Inhibitor on One-Carbon Metabolism in Parkinson's Disease: A Meta-Analysis. Nutrients. 2023;15.
Ju IG, Son SY, Lee S, Im H, Huh E, Eo H, et al. Protective effects of CCL01 against Abeta-induced neurotoxicity in 5xFAD transgenic mouse model of Alzheimer's disease. Biomed Pharmacother. 2023;158:114105.
Huh E, Choi JG, Lee MY, Kim JH, Choi Y, Ju IG, Eo H, et al. Peripheral metabolic alterations associated with pathological manifestations of Parkinson's disease in gut-brain axis-based mouse model. Front Mol Neurosci. 2023;16:1201073.
Eo H, Kim SH, Ju IG, Huh E, Kim S, Choi JG, et al. Longan extract suppresses food intake through regulation of POMC/AgRP neuronal activities and endoplasmic reticulum stress in hypothalamus of db/db mice. Front Nutr. 2023;10:1143613.
2022
Kim M, Eo H, Lim JG, Lim H, Lim Y. Can Low-Dose of Dietary Vitamin E Supplementation Reduce Exercise-Induced Muscle Damage and Oxidative Stress? A Meta-Analysis of Randomized Controlled Trials. Nutrients. 2022;14.
Eo H, Valentine RJ. Saturated Fatty Acid-Induced Endoplasmic Reticulum Stress and Insulin Resistance Are Prevented by Imoxin in C2C12 Myotubes. Front Physiol. 2022;13:842819.
Eo H, Lee S, Kim SH, Ju IG, Huh E, Lim J, et al. Petasites japonicus leaf extract inhibits Alzheimer's-like pathology through suppression of neuroinflammation. Food Funct. 2022;13:10811-22.
2021
Eo H, Valentine RJ. Imoxin inhibits tunicamycin-induced endoplasmic reticulum stress and restores insulin signaling in C2C12 myotubes. Am J Physiol Cell Physiol. 2021;321:C221-C9.
2020
Eo H, Reed CH, Valentine RJ. Imoxin prevents dexamethasone-induced promotion of muscle-specific E3 ubiquitin ligases and stimulates anabolic signaling in C2C12 myotubes. Biomed Pharmacother. 2020;128:110238.
2019
Eo H, Kwon Y, Huh E, Sim Y, Choi JG, Jeong JS, et al. Protective effects of DA-9805 on dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity in the models of Parkinson's disease. Biomed Pharmacother. 2019;117:109184.
Eo H, Huh E, Sim Y, Oh MS. Ukgansan protects dopaminergic neurons from 6-hydroxydopamine neurotoxicity via activation of the nuclear factor (erythroid-derived 2)-like 2 factor signaling pathway. Neurochem Int. 2019;122:208-15.
2018
Valentine RJ, Jefferson MA, Kohut ML, Eo H. Imoxin attenuates LPS-induced inflammation and MuRF1 expression in mouse skeletal muscle. Physiol Rep. 2018;6:e13941.
Choi JG, Kim N, Ju IG, Eo H, Lim SM, Jang SE, et al. Oral administration of Proteus mirabilis damages dopaminergic neurons and motor functions in mice. Sci Rep. 2018;8:1275.
2017
Sim Y, Park G, Eo H, Huh E, Gu PS, Hong SP, et al. Protective effects of a herbal extract combination of Bupleurum falcatum, Paeonia suffruticosa, and Angelica dahurica against MPTP-induced neurotoxicity via regulation of nuclear receptor-related 1 protein. Neuroscience. 2017;340:166-75.
Eo H, Park JE, Jeon YJ, Lim Y. Ameliorative Effect of Ecklonia cava Polyphenol Extract on Renal Inflammation Associated with Aberrant Energy Metabolism and Oxidative Stress in High Fat Diet-Induced Obese Mice. J Agric Food Chem. 2017;65:3811-8.
2016
Shin H, Eo H, Lim Y. Similarities and differences between alpha-tocopherol and gamma-tocopherol in amelioration of inflammation, oxidative stress and pre-fibrosis in hyperglycemia induced acute kidney inflammation. Nutr Res Pract. 2016;10:33-41.
Eo H, Lim Y. Combined Mulberry Leaf and Fruit Extract Improved Early Stage of Cutaneous Wound Healing in High-Fat Diet-Induced Obese Mice. J Med Food. 2016;19:161-9.
2015
Eo H, Jeon Y-j, Lee M, Lim Y. Brown Alga Ecklonia cava Polyphenol Extract Ameliorates Hepatic Lipogenesis, Oxidative Stress, and Inflammation by Activation of AMPK and SIRT1 in High-Fat Diet-Induced Obese Mice. Journal of Agricultural and Food Chemistry. 2015;63:349-59.
Ann J-Y, Eo H, Lim Y. Mulberry leaves (Morus alba L.) ameliorate obesity-induced hepatic lipogenesis, fibrosis, and oxidative stress in high-fat diet-fed mice. Genes & Nutrition. 2015;10:46.
2014
Valacchi G, Belmonte G, Miracco C, Eo H, Lim Y. Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice. Nutr Res Pract. 2014;8:20-6.